Round 1 : 1 player drafted
Detroit Matthew Stafford QB
  Georgia 6-2 225
Round 1 : 2 player drafted
St. Louis Aaron Curry LB
  Wake Forest 6-2 247
Round 1 : 3 player drafted
Kansas City Eugene Monroe T
  Virginia 6-5 310
Round 1 : 4 player drafted
Seattle Jason Smith T
  Baylor 6-5 310
Round 1 : 5 player drafted
Cleveland Andre Smith T
  Alabama 6-4 332
Round 1 : 6 player drafted
Cincinnati Brian Orakpo DE
  Texas 6-3 263
Round 1 : 7 player drafted
Oakland Michael Crabtree WR
  Texas Tech 6-2 215
Round 1 : 8 player drafted
Jacksonville Jeremy Maclin WR
  Missouri 6-0 200
Round 1 : 9 player drafted
Green Bay B.J. Raji DT
  Boston College 6-1 323
Round 1 : 10 player drafted
San Francisco Everette Brown LB
  Florida State 6-2 256
Round 1 : 11 player drafted
Buffalo Brandon Pettigrew TE
  Oklahoma State 6-6 260
Round 1 : 12 player drafted
Denver Mark Sanchez QB
  USC 6-2 225
Round 1 : 13 player drafted
Washington Michael Oher T
  Mississippi 6-5 310
Round 1 : 14 player drafted
New Orleans Vontae Davis CB
  Illinois 6-0 203
Round 1 : 15 player drafted
Houston Malcolm Jenkins CB
  Ohio State 6-1 201
Round 1 : 16 player drafted
San Diego Eben Britton T
  Arizona 6-6 310
Round 1 : 17 player drafted
NY Jets Josh Freeman QB
  Kansas State 6-6 248
Round 1 : 18 player drafted
Denver Peria Jerry DT
  Mississippi 6-2 290
Round 1 : 19 player drafted
Tampa Bay Larry English LB
  No. Illinois 6-2 254
Round 1 : 20 player drafted
Detroit William Beatty T
  Connecticut 6-6 307
Round 1 : 21 player drafted
Philadelphia Knowshon Moreno TB
  Georgia 5-10 217
Round 1 : 22 player drafted
Minnesota Percy Harvin WR
  Florida 5-11 195
Round 1 : 23 player drafted
New England Alphonso Smith CB
  Wake Forest 5-9 191
Round 1 : 24 player drafted
Atlanta Rey Maualuga IB
  USC 6-3 255
Round 1 : 25 player drafted
Miami Darrius Heyward-Bey WR
  Maryland 6-2 206
Round 1 : 26 player drafted
Baltimore Robert Ayers DE
  Tennessee 6-3 273
Round 1 : 27 player drafted
Indianapolis LeSean McCoy TB
  Pittsburgh 5-11 210
Round 1 : 28 player drafted
Philadelphia Jared Cook TE
  South Carolina 6-5 245
Round 1 : 29 player drafted
NY Giants Hakeem Nicks WR
  North Carolina 6-1 215
Round 1 : 30 player drafted
Tennessee Darius Butler CB
  Connecticut 5-11 178
Round 1 : 31 player drafted
Arizona Chris "Beanie" Wells TB
  Ohio State 6-1 235
Round 1 : 32 player drafted
Pittsburgh Jarron Gilbert DT
  San Jose State 6-6 288